• Delivering Quality Research

    For developing a centre-of-excellence in Translational Genomics & Bioinformatics

  • Tackling societal problems

    Through multiomics and systems biology

  • Developing skilled human resources

    For cutting-edge research in Bioinformatics and computational biology

RESEARCH PROGRAMS

Development of Potential RNA based Therapeutic Agents



MicroRNAs (miRNAs) targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various diseases. Our group is trying to decipher the mechanism of action, the ability to function as master regulators of the genome and an apparent lack of adverse events in normal tissue,which make microRNA a promising technology for current and future therapeutic development. Ineterestingly, we are involved in using this tiny riboswitches as a targeted immunomodulators for various discorders

Development of DNA based Diagnostics for important societal health problem



Understanding the disease architecture and possible multiomics and systems biology interventions towards the discovery of new molecular targets for effective vaccine candidates. Our group is trying to develop a complete cascade of information on diseases like leptospirosis, MDR and various Cancers and make an attempt to understand the metadata of genomes, epigenomes and proteomes towards host-pathogen relationship & molecular pathways involved, which may translate into valuable products for the society.

Translational Bioinformatics & Systems Biology for Environment and Industrial solutions



Currently, Biotechnology and Life sciences sector is completely dependent on the Bioinformatics as a major driver. There is a huge demand of need-based tool/software/pipeline/database for each type of biological data analysis and contributes major market as well. It will help to facilitate processing, analysis, and management of large data sets for human welfare. Our group is trying to look into the Big Data of bioresources and analyse extensively in all levels of genomics, metabolomics and proteomics for valuable enzymes, genes, proteins and metabolites which may use for various industrial and environmental applications.

Research Group

 

Dr. Jayashankar Das

Scientist D & Joint Director (Group Leader)
Email:- jd2-gbrc[at]gujarat[dot]gov[dot]in ; jayshankardas[at]gmail[dot]com

Research Areas :


 

Molecular Therapeutics


  • Development of antagomiR & molecular modulators as targeted cancer therapy
  • Understanding dynamism of miRNAs in human regulatome for development of molecular therapeutics
  • Understanding Genomics and proteomics of host-pathogen interaction in Leptospirosis for development of Vaccine candidate
  • Development of DNA based biosensor for infectious diseases

Environmental Genomics


  • Development of Omics based treatment technology for textile effluent
  • Development of enzyme based Bioremediation technology for solild waste management through metagenomics
  • Understanding extreme microbial pathways from extreme environment for novel catalytic properties

Bioinformatics & Systems Biology


  • Understanding miRNA – Gene – Pathways interactions via Big Data Oncoinformatics and Systems Biology
  • Translational Bioinformatics for discovery of novel molecules from extreme environment
  • Development of database, software, pipelines for highthroughput genomics, metagenomics and Proteomics analysis
  • Genomic reconstructions for providing better environmental problem solutions

Dr. Shivarudrappa B


Scientist B

Interest:- Environmental Biotechnological applications for solid waste, Textile, paper and pulp effluent based on Omics Technology. Understanding small RNAs directed to Molecular Therapeutics. To identify protein-RNA networks control genes involved in bacterial pathogenesis. Molecular biosensors, interests are in enzyme, DNA and RNA based biosensors. Marine Biotechnology.

Email:- scib3-gbrc[at]gujarat[dot]gov[dot]in ; rudra8282[at]gmail[dot]com


 

Dr. Priyanka Sharma


Scientist B

Interest:- Nucleic acid based vaccine/probe designing, biological networks, nutrigenomics, nutraceutical based solutions for cancer diagnostics & therapeutics, multi-drug resistance and infection biology.

Email :- scib4-gbrc[at]gujarat[dot]gov[dot]in ; mailsharma.p[at]gmail[dot]com


 

Zuber Saiyad


Research Associate

Interest:- Marine & Environmental Metagenomics, System Administration (Linux) & Troubleshooting, HPC & Cloud Computing


 

Dr. Prabhakar Pandit


Research Associate

Interest:- Environmental genomics, Omics based bioremediation technologies for Municipal and industrial waste, bacterial pathogen genomics, Diagnostics and Therapeutics


 

Inayat Shaikh


Research Associate

Interest:- Biomarker and molecular therapeutics for cancer, Oncoinformatics, Database & Tool Development


 

Garima Ayachit


Research Associate

Interest:- Omics of Plant and Human molecular systems, development of intelligent systems for molecular problems


 

Preeti Sharma


Senior Research Fellow

Interest:- Plant based miRNA solutions for cancer therapeutics


 

Shruti Beriwal


Junior Research Fellow

Interest:- Structural & Comparative Genomics of infectious diseases ; Transcriptomics.


 

Afzal Ansari


Junior Research Fellow

Interest:- Phlyogenomics, Cancer informatics, Software Development


 

Swapnil Kumar


Junior Research Fellow

Interest:- Network theory & dynamics of biological networks; miRNA impact on disease modules


 

Dinesh Kumar


Junior Research Fellow

Interest:- Environmental Genomics, Systems Biology and Meta-Omics


 

Snehkant Lata


Junior Research Fellow

Interest:- Immuno-informatics; DNA/Peptide based vaccine designing


 

Vibhisha Senjaliya


Junior Research Fellow

Interest:- Role of Membrane transporters & Post-translation changes in disease pathogenesis


 

Nikhil Padhiyar


Junior Research Fellow

Interest:- Development and Integration of Database, Software and Pipeline for Environmental Genomics, Python programming


 

Deven Bhatt


Junior Research Fellow

Interest:- Development and Integration of Database, Software and Pipeline for Environmental Genomics


 

Amit Kumar


Junior Research Fellow

Interest:- Environmental genomics, Bioremediation of municipal plastic waste


 

Zarna Patel


Junior Research Fellow

Interest:- Environmental genomics, Bioremediation of municipal cellulosic waste , Molecular Diagnostics & Therapeutics


 

Monika Gandhi


Junior Research Fellow

Interest:- Nucleic acid based probe development for cancer Diagnostics


 

Opportunities

We value your research Interest in collaborating with us and welcome any opportunities to explore the possibilities of working with you. Please feel free to drop an Interest for joint program/bilateral projects/postdoc to jd2-gbrc[at]gujarat[dot]gov[dot]in

SERB/DST/DBT/CSIR/ICMR young scientists and Post doctoral researchers are encouraged to apply for joining the group through a funding agency

TRAINING & WORKSHOP

We provide hands-on-trainning to faculties in the areas of Genomics, Transcriptomics, systems biology, Network biology, etc. from time to time. Also, we committed to produce highly skilled manpower for NGS data analysis, development of software/pipeline/database which will be useful for addressing biological problems. We provide training to all level of students and scholars including B.Sc., B.E., B.Tech., M.Sc., M.Tech., M.Phil., Ph.D and Postdoc. For training and dissertation keep visiting GSBTM website.

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Areas
Multiomics (Genomics, Proteomics, Transcriptomics, metabolomics), Structural Biology, Systems Biology, Synthetic biology, DNA Computing, Biostatistics, Computational Biology, Big Data analytics.

Our Location

Contact Us


Director

Gujarat Biotechnology Research Centre

Department of Science & Technology

Government of Gujarat

Block-B & D, 6th floor,

M. S. Building, Sector 11,

Gandhinagar,

Gujarat 382011, India

Call:+91 (079)23258500

Email: info-gbrc[at]gujarat[dot]gov[dot]in

Dr. Jayashankar Das

Scientist-D & Joint Director

Gujarat Biotechnology Research Centre

Department of Science & Technology

Government of Gujarat

Block-B & D, 6th floor,

M. S. Building, Sector 11,

Gandhinagar,

Gujarat 382011, India

Call:+91(079)23258500/23252166

Email: jd2-gbrc[at]gujarat[dot]gov[dot]in